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Wednesday 6 March 2013

Memantine for alzheimer's dementia


Does memantine work in Alzheimer patients?

Alzheimer’s dementia is a very unpleasant chronic medical disorder that brings a lot of anguish to everyone looking after the involved patient. There are no good methods to make an early diagnosis and to make matters worse; there is no good medical treatment.

The acetylcholine-esterase inhibitor, such as Aricept, has not proven to be effective in clinical trials. In the last decade, several novel drugs have been developed to treat AD, of which one of them is memantine (Namenda).

Today many physicians prescribe memantine for mild dementia-however; its efficacy has only been supported by trials supported by the manufacturer.

Current research indicates that memantine is not a drug of choice for mild dementia. Moreover, the drugs benefits for moderate dementia are very mild.

Another important factor that has substantial importance in today's economy is the price of Memantine. Depending on where you buy the drug, each pill can cost anywhere from $2-$4. Memantine is supposed to be taken twice a day and this amount to $120-$240 a month.

Finally, there is no way of knowing if the drug will work. In the UK, the National Institute for Clinical Excellence recently opposed the use of Memantine because they felt the costs and it side effects clearly outweighed any possible benefit. 

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